Anti-Recombinant-CCL23/MIP-3/MPIF-1 antibody [RM1Z40] (STJA0024915)

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STJA0024915
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Host: Rabbit
Applications: IHC/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-C-C Motif Chemokine 23 is suitable for use in Immunohistochemistry and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM1Z40
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IHC: 1:100-1:200
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: CCL23
Gene ID: 6368
Uniprot ID: CCL23_HUMAN
Post Translational Modifications The N-terminal is proteolytically cleaved by proteases associated with inflammatory responses. The processed forms, CCL23(19-99), CCL23(22-99), CCL23(27-99) and CCL23(30-99) exhibit increase in CCR1-mediated signaling and chemotaxis assays in vitro.
Function Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than CCL23.
Protein Name C-C Motif Chemokine 23
Ck-Beta-8
Ckb-8
Macrophage Inflammatory Protein 3
Mip-3
Myeloid Progenitor Inhibitory Factor 1
Mpif-1
Small-Inducible Cytokine A23 Cleaved Into - Ccl23(19-99 - Ccl23(22-99 - Ccl23(27-99 - Ccl23(30-99
Database Links Reactome: R-HSA-416476 P55773-2
Reactome: R-HSA-418594 P55773-2
Reactome: R-HSA-444473 P55773-2
Cellular Localisation Secreted
Alternative Antibody Names Anti-C-C Motif Chemokine 23 antibody
Anti-Ck-Beta-8 antibody
Anti-Ckb-8 antibody
Anti-Macrophage Inflammatory Protein 3 antibody
Anti-Mip-3 antibody
Anti-Myeloid Progenitor Inhibitory Factor 1 antibody
Anti-Mpif-1 antibody
Anti-Small-Inducible Cytokine A23 Cleaved Into - Ccl23(19-99 - Ccl23(22-99 - Ccl23(27-99 - Ccl23(30-99 antibody
Anti-CCL23 antibody
Anti-MIP3 antibody
Anti-MPIF1 antibody
Anti-SCYA23 antibody

Information sourced from Uniprot.org

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