| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RARRES3 (1-135) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PLAAT4 |
| Gene ID: |
5920 |
| Uniprot ID: |
PLAT4_HUMAN |
| Immunogen Region: |
1-135 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human RARRES3 (NP_004576.2). |
| Immunogen Sequence: |
MASPHQEPKPGDLIEIFRLG YEHWALYIGDGYVIHLAPPS EYPGAGSSSVFSVLSNSAEV KRERLEDVVGGCCYRVNNSL DHEYQPRPVEVIISSAKEMV GQKMKYSIVSRNCEHFVTQL RYGKSRCKQVEKAKV |
| Tissue Specificity | Widely expressed. |
| Function | Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1) and A2 (PLA2), catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. For most substrates, PLA1 activity is much higher than PLA2 activity. Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid. Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE), which serves as precursor for N-acylethanolamines (NAEs). Promotes keratinocyte differentiation via activation of TGM1. |
| Protein Name | Phospholipase A And Acyltransferase 4 Hras-Like Suppressor 4Hrsl4Rar-Responsive Protein Tig3Retinoic Acid Receptor Responder Protein 3Retinoid-Inducible Gene 1 ProteinTazarotene-Induced Gene 3 Protein |
| Database Links | Reactome: R-HSA-1482839 |
| Cellular Localisation | MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Phospholipase A And Acyltransferase 4 antibodyAnti-Hras-Like Suppressor 4 antibodyAnti-Hrsl4 antibodyAnti-Rar-Responsive Protein Tig3 antibodyAnti-Retinoic Acid Receptor Responder Protein 3 antibodyAnti-Retinoid-Inducible Gene 1 Protein antibodyAnti-Tazarotene-Induced Gene 3 Protein antibodyAnti-PLAAT4 antibodyAnti-RARRES3 antibodyAnti-RIG1 antibodyAnti-TIG3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
