Anti-PSIP1 nanobody [SAA1182] (STJN000050)

SKU:
STJN000050
£378.50 - £1,632.50
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Host: Alpaca
Applications: ELISA/SPR
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-Pc4 And Sfrs1-Interacting Protein is suitable for use in ELISA and SPR research applications.
Clonality : Monoclonal
Clone ID : SAA1182
Conjugation: Unconjugated
Isotype: VHH-8His-Cys-tag
Formulation: 0.01M PBS, pH 7.4.
Purification: Purified by Nickel column.
Concentration: 1 mg/mL
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol: PSIP1
Gene ID: 11168
Uniprot ID: PSIP1_HUMAN
Post Translational Modifications Citrullinated by PADI4.
Function Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.
Protein Name Pc4 And Sfrs1-Interacting Protein
Cll-Associated Antigen Kw-7
Dense Fine Speckles 70 Kda Protein
Dfs 70
Lens Epithelium-Derived Growth Factor
Transcriptional Coactivator P75/P52
Database Links Reactome: R-HSA-162592
Reactome: R-HSA-164843
Reactome: R-HSA-175567
Reactome: R-HSA-177539
Reactome: R-HSA-180689
Reactome: R-HSA-180910
Reactome: R-HSA-9772755
Cellular Localisation Nucleus
Remains Chromatin-Associated Throughout The Cell Cycle
Alternative Nanobody Names Anti-Pc4 And Sfrs1-Interacting Protein nanobody
Anti-Cll-Associated Antigen Kw-7 nanobody
Anti-Dense Fine Speckles 70 Kda Protein nanobody
Anti-Dfs 70 nanobody
Anti-Lens Epithelium-Derived Growth Factor nanobody
Anti-Transcriptional Coactivator P75/P52 nanobody
Anti-PSIP1 nanobody
Anti-DFS70 nanobody
Anti-LEDGF nanobody
Anti-PSIP2 nanobody

Information sourced from Uniprot.org