| Post Translational Modifications | Occurs in a single-chain form and a two-chain form, produced by proteolytic cleavage after Arg-122. Sulfation at Tyr-154 increases selectivity towards basic versus apolar residues at the P2' position of inhibitors that bind in a substrate-like fashion. Although the increase in selectivity is relatively small, it may facilitate digestion of a broader range of dietary proteins. |
| Function | Has activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all of these substrates. |
| Protein Name | Serine Protease 1Anionic Trypsin IAnionic Trypsin-IBeta-TrypsinCationic TrypsinogenPretrypsinogen ITrypsin ITrypsin-1 Cleaved Into - Alpha-Trypsin Chain 1 - Alpha-Trypsin Chain 2 |
| Database Links | Reactome: R-HSA-1592389Reactome: R-HSA-9758881 |
| Cellular Localisation | SecretedExtracellular Space |
| Alternative Antibody Names | Anti-Serine Protease 1 antibodyAnti-Anionic Trypsin I antibodyAnti-Anionic Trypsin-I antibodyAnti-Beta-Trypsin antibodyAnti-Cationic Trypsinogen antibodyAnti-Pretrypsinogen I antibodyAnti-Trypsin I antibodyAnti-Trypsin-1 Cleaved Into - Alpha-Trypsin Chain 1 - Alpha-Trypsin Chain 2 antibodyAnti-PRSS1 antibodyAnti-TRP1 antibodyAnti-TRY1 antibodyAnti-TRYP1 antibody |
Information sourced from Uniprot.org
