Host: | Mouse |
Applications: | ELISA/FC |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Short Description : | Mouse monoclonal antibody anti-Prolactin Receptor is suitable for use in ELISA and Flow Cytometry research applications. |
Clonality : | Monoclonal |
Clone ID : | SAA2060 |
Conjugation: | FITC |
Isotype: | IgG2ak |
Formulation: | 0.01M PBS, pH 7.4, 02% BSA, 0.05% Proclin 300 |
Purification: | Purified |
Concentration: | 05 mg/mL |
Storage Instruction: | Store at 4°C for 12 months Protect from light Do not freeze |
Gene Symbol: | PRLR |
Gene ID: | 5618 |
Uniprot ID: | PRLR_HUMAN |
Function | This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling. |
Protein Name | Prolactin ReceptorPrl-R |
Database Links | Reactome: R-HSA-1170546Reactome: R-HSA-982772 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinIsoform 7: Secreted |
Alternative Antibody Names | Anti-Prolactin Receptor antibodyAnti-Prl-R antibodyAnti-PRLR antibody |
Information sourced from Uniprot.org