| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-PPP2R5A (50-130) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPP2R5A |
| Gene ID: | 5525 |
| Uniprot ID: | 2A5A_HUMAN |
| Immunogen Region: | 50-130 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-130 of human PP2A-B56 Alpha/PR61A/PP2A-B56 Alpha/PR61A/PPP2R5A (NP_006234.1). |
| Immunogen Sequence: | QAELHPLPQLKDATSNEQQE LFCQKLQQCCILFDFMDSVS DLKSKEIKRATLNELVEYVS TNRGVIVESAYSDIVKMISA N |
| Tissue Specificity | Widely expressed with the highest expression in heart and skeletal muscle. |
| Post Translational Modifications | Phosphorylated on serine residues. |
| Function | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. |
| Protein Name | Serine/Threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Alpha IsoformPp2a B Subunit Isoform B'-AlphaPp2a B Subunit Isoform B56-AlphaPp2a B Subunit Isoform Pr61-AlphaPr61alphaPp2a B Subunit Isoform R5-Alpha |
| Database Links | Reactome: R-HSA-141444Reactome: R-HSA-195253Reactome: R-HSA-196299Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-389513Reactome: R-HSA-432142Reactome: R-HSA-4641262Reactome: R-HSA-5339716Reactome: R-HSA-5358747Reactome: R-HSA-5358749Reactome: R-HSA-5358751Reactome: R-HSA-5358752Reactome: R-HSA-5467337Reactome: R-HSA-5467340Reactome: R-HSA-5467348Reactome: R-HSA-5663220Reactome: R-HSA-5673000Reactome: R-HSA-5675221Reactome: R-HSA-6811558Reactome: R-HSA-68877Reactome: R-HSA-9648025 |
| Cellular Localisation | CytoplasmNucleusChromosomeCentromereFrom Mitotic Prophase To MetaphaseLocalizes At The Inner Centromere Between A Pair Of Sister KinetochoresDecreased Expression At The Onset Of Anaphase |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Alpha Isoform antibodyAnti-Pp2a B Subunit Isoform B'-Alpha antibodyAnti-Pp2a B Subunit Isoform B56-Alpha antibodyAnti-Pp2a B Subunit Isoform Pr61-Alpha antibodyAnti-Pr61alpha antibodyAnti-Pp2a B Subunit Isoform R5-Alpha antibodyAnti-PPP2R5A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
