Anti-POU2F2 antibody (250-350 aa) [PT0202] (STJ196799)

SKU:
STJ196799

Current Stock:
Host: Mouse
Applications: IHC/IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-POU domain, class 2, transcription factor 2 (250-350 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: PT0202
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range: IHC-P 1:100-500
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: POU2F2
Gene ID: 5452
Uniprot ID: PO2F2_HUMAN
Immunogen Region: 250-350 aa
Specificity: This antibody detects endogenous levels of human Oct-2. Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section
Immunogen: Synthesized peptide derived from the human Oct-2 at the amino acid range 250-350
Function Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates IL6 expression in B cells with POU2AF1. Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5: Activates the U2 small nuclear RNA (snRNA) promoter.
Protein Name Pou Domain - Class 2 - Transcription Factor 2
Lymphoid-Restricted Immunoglobulin Octamer-Binding Protein Nf-A2
Octamer-Binding Protein 2
Oct-2
Octamer-Binding Transcription Factor 2
Otf-2
Database Links Reactome: R-HSA-6807505
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Pou Domain - Class 2 - Transcription Factor 2 antibody
Anti-Lymphoid-Restricted Immunoglobulin Octamer-Binding Protein Nf-A2 antibody
Anti-Octamer-Binding Protein 2 antibody
Anti-Oct-2 antibody
Anti-Octamer-Binding Transcription Factor 2 antibody
Anti-Otf-2 antibody
Anti-POU2F2 antibody
Anti-OCT2 antibody
Anti-OTF2 antibody

Information sourced from Uniprot.org

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