| Host: |
Rabbit |
| Applications: |
IF |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-POMGNT2 (301-580) is suitable for use in Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IF 1:20-1:50 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
POMGNT2 |
| Gene ID: |
84892 |
| Uniprot ID: |
PMGT2_HUMAN |
| Immunogen Region: |
301-580 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 301-580 of human POMGNT2 (NP_116195.2). |
| Immunogen Sequence: |
LNEAELLLALAQEFQMKTVT VSLEDHTFADVVRLVSNASM LVSMHGAQLVTTLFLPRGAT VVELFPYAVNPDHYTPYKTL AMLPGMDLQYVAWRNMMPEN TVTHPERPWDQGGITHLDRA EQARILQSREVPRHLCCRNP EWLFRIYQDTKVDIPSLIQT IRRVVKGRPGPRKQKWTVGL YPGKVREARCQASVHGASEA RLTVSWQIPWNLKYLKVREV KYEVWLQEQGENTYVPYIL |
| Tissue Specificity | Highly expressed in the brain, muscle, heart, and kidney in both fetus and adult. In the brain, highest expression in the cortex and cerebellum. Highly expressed in the pancreas. |
| Function | O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein. Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. |
| Protein Name | Protein O-Linked-Mannose Beta-1 -4-N-Acetylglucosaminyltransferase 2Pomgnt2Extracellular O-Linked N-Acetylglucosamine Transferase-LikeGlycosyltransferase-Like Domain-Containing Protein 2 |
| Database Links | Reactome: R-HSA-5173105 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Protein O-Linked-Mannose Beta-1 -4-N-Acetylglucosaminyltransferase 2 antibodyAnti-Pomgnt2 antibodyAnti-Extracellular O-Linked N-Acetylglucosamine Transferase-Like antibodyAnti-Glycosyltransferase-Like Domain-Containing Protein 2 antibodyAnti-POMGNT2 antibodyAnti-AGO61 antibodyAnti-C3orf39 antibodyAnti-EOGTL antibodyAnti-GTDC2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
