Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-PLD1 (875-1036) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PLD1 |
Gene ID: |
5337 |
Uniprot ID: |
PLD1_HUMAN |
Immunogen Region: |
875-1036 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 875-1036 of human PLD1 (NP_001123553.1). |
Immunogen Sequence: |
NINDRSMLGKRDSEMAVIVQ DTETVPSVMDGKEYQAGRFA RGLRLQCFRVVLGYLDDPSE DIQDPVSDKFFKEVWVSTAA RNATIYDKVFRCLPNDEVHN LIQLRDFINKPVLAKEDPIR AEEELKKIRGFLVQFPFYFL SEESLLPSVGTKEAIVPMEV WT |
Tissue Specificity | Expressed abundantly in the pancreas and heart and at high levels in brain, placenta, spleen, uterus and small intestine. |
Function | Function as phospholipase selective for phosphatidylcholine. Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic. |
Protein Name | Phospholipase D1Pld 1Hpld1Choline Phosphatase 1Phosphatidylcholine-Hydrolyzing Phospholipase D1 |
Database Links | Reactome: R-HSA-1483148Reactome: R-HSA-1483166Reactome: R-HSA-2029485Reactome: R-HSA-6798695Reactome: R-HSA-8980692Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9013408 |
Cellular Localisation | CytoplasmPerinuclear RegionEndoplasmic Reticulum MembraneLipid-AnchorCytoplasmic SideGolgi Apparatus MembraneLate Endosome Membrane |
Alternative Antibody Names | Anti-Phospholipase D1 antibodyAnti-Pld 1 antibodyAnti-Hpld1 antibodyAnti-Choline Phosphatase 1 antibodyAnti-Phosphatidylcholine-Hydrolyzing Phospholipase D1 antibodyAnti-PLD1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance