Immunofluorescence analysis of U-87MG cells using uPAR/U-PAR Rabbit monoclonal antibody (STJ11105088) at dilution of 1:300 (40x lens). Blue: DAPI for nuclear staining.

Anti-PLAUR antibody [S5088RM] (STJ11105088)

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STJ11105088
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Host: Rabbit
Applications: IF/ICC/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : S5088RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: IF/ICC:1:100-1:500
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PLAUR
Gene ID: 5329
Uniprot ID: UPAR_HUMAN
Specificity: Recombinant protein of human uPAR/U-PAR.
Immunogen Sequence: LRCMQCKTNGDCRVEECALG QDLCRTTIVRLWEEGEELEL VEKSCTHSEKTNRTLSYRTG LKITSLTEVVCGLDLCNQGN SGRAVTYSRSRYLECISCGS SDMSCERGRHQSLQCRSPEE QCLDVVTHWIQEGEEGRPKD DRHLRGCGYLPGCPGSNGFH NNDTFHFLKCCNTTKCNEGP ILELENLPQNGRQCYSCKGN STHGCSSEETFLIDCRGPMN QCLVATGTHEPKNQSYMVR
Tissue Specificity Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.
Function Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Protein Name Urokinase Plasminogen Activator Surface Receptor
U-Par
Upar
Monocyte Activation Antigen Mo3
Cd Antigen Cd87
Database Links Reactome: R-HSA-162791
Reactome: R-HSA-6798695
Reactome: R-HSA-75205
Cellular Localisation Cell Membrane
Cell Projection
Invadopodium Membrane
Colocalized With Fap (Seprase) Preferentially At The Cell Surface Of Invadopodia Membrane In A Cytoskeleton-
Integrin- And Vitronectin-Dependent Manner
Isoform 1: Cell Membrane
Lipid-Anchor
Gpi-Anchor
Isoform 2: Secreted
Alternative Antibody Names Anti-Urokinase Plasminogen Activator Surface Receptor antibody
Anti-U-Par antibody
Anti-Upar antibody
Anti-Monocyte Activation Antigen Mo3 antibody
Anti-Cd Antigen Cd87 antibody
Anti-PLAUR antibody
Anti-MO3 antibody
Anti-UPAR antibody

Information sourced from Uniprot.org

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