| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PHYH |
| Gene ID: | 5264 |
| Uniprot ID: | PAHX_HUMAN |
| Immunogen Region: | 1-338 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-338 of human PHYH (NP_006205.1). |
| Immunogen Sequence: | MEQLRAAARLQIVLGHLGRP SAGAVVAHPTSGTISSASFH PQQFQYTLDNNVLTLEQRKF YEENGFLVIKNLVPDADIQR FRNEFEKICRKEVKPLGLTV MRDVTISKSEYAPSEKMITK VQDFQEDKELFRYCTLPEIL KYVECFTGPNIMAMHTMLIN KPPDSGKKTSRHPLHQDLHY FPFRPSDLIVCAWTAMEHIS RNNGCLVVLPGTHKGSLKPH DYPKWEGGVNKMFHGIQDY |
| Tissue Specificity | Expressed in liver, kidney, and T-cells, but not in spleen, brain, heart, lung and skeletal muscle. |
| Function | Catalyzes the 2-hydroxylation of not only racemic phytanoyl-CoA and the isomers of 3-methylhexadecanoyl-CoA, but also a variety of other mono-branched 3-methylacyl-CoA esters (with a chain length of at least seven carbon atoms) and straight-chain acyl-CoA esters (with a chain length longer than four carbon atoms). Does not hydroxylate long and very long straight chain acyl-CoAs or 2-methyl- and 4-methyl-branched acyl-CoAs. |
| Protein Name | Phytanoyl-Coa Dioxygenase - PeroxisomalPhytanic Acid OxidasePhytanoyl-Coa Alpha-HydroxylasePhyh |
| Database Links | Reactome: R-HSA-389599Reactome: R-HSA-9033241Reactome: R-HSA-9033500 |
| Cellular Localisation | Peroxisome |
| Alternative Antibody Names | Anti-Phytanoyl-Coa Dioxygenase - Peroxisomal antibodyAnti-Phytanic Acid Oxidase antibodyAnti-Phytanoyl-Coa Alpha-Hydroxylase antibodyAnti-Phyh antibodyAnti-PHYH antibodyAnti-PAHX antibody |
Information sourced from Uniprot.org