| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-P3H4 (338-437) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
P3H4 |
| Gene ID: |
10609 |
| Uniprot ID: |
SC65_HUMAN |
| Immunogen Region: |
338-437 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 338-437 of human P3H4 (NP_006446.1). |
| Immunogen Sequence: |
FHRARWGLEEEDFQPREEAM LYHNQTAELRELLEFTHMYL QSDDEMELEETEPPLEPEDA LSDAEFEGEGDYEEGMYADW WQEPDAKGDEAEAEPEPELA |
| Tissue Specificity | Detected in fibroblasts (at protein level). Detected in spleen, prostate, testis, ovary, colon, pancreas, kidney, placenta and heart. |
| Function | Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linking of collagen fibrils. Required for normal bone density and normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly. |
| Protein Name | Endoplasmic Reticulum Protein Sc65Leprecan-Like Protein 4Nucleolar Autoantigen No55Prolyl 3-Hydroxylase Family Member 4Synaptonemal Complex Protein Sc65 |
| Cellular Localisation | Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Endoplasmic Reticulum Protein Sc65 antibodyAnti-Leprecan-Like Protein 4 antibodyAnti-Nucleolar Autoantigen No55 antibodyAnti-Prolyl 3-Hydroxylase Family Member 4 antibodyAnti-Synaptonemal Complex Protein Sc65 antibodyAnti-P3H4 antibodyAnti-LEPREL4 antibodyAnti-NOL55 antibodyAnti-SC65 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
