Post Translational Modifications | N-glycosylated. |
Function | Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. |
Protein Name | Placenta Growth FactorPlgf |
Database Links | Reactome: R-HSA-194313Reactome: R-HSA-195399 |
Cellular Localisation | SecretedThe Three Isoforms Are Secreted But Plgf-2 Appears To Remain Cell Attached Unless Released By Heparin |
Alternative Antibody Names | Anti-Placenta Growth Factor antibodyAnti-Plgf antibodyAnti-PGF antibodyAnti-PGFL antibodyAnti-PLGF antibody |
Information sourced from Uniprot.org