| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PDS5A (1020-1120) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PDS5A |
| Gene ID: |
23244 |
| Uniprot ID: |
PDS5A_HUMAN |
| Immunogen Region: |
1020-1120 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1020-1120 of human PDS5A (Q29RF7). |
| Immunogen Sequence: |
DVDQLRDIKECLWFMLEVLM TKNENNSHAFMKKMAENIKL TRDAQSPDESKTNEKLYTVC DVALCVINSKSALCNADSPK DPVLPMKFFTQPEKDFCNDK S |
| Tissue Specificity | Highest level in colon. Low levels in lung, ovary, breast and kidney. Reduced level in renal tumor tissue. Isoform 2 is expressed in kidney. |
| Function | Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. |
| Protein Name | Sister Chromatid Cohesion Protein Pds5 Homolog ACell Proliferation-Inducing Gene 54 ProteinSister Chromatid Cohesion Protein 112Scc-112 |
| Database Links | Reactome: R-HSA-2467813Reactome: R-HSA-2468052Reactome: R-HSA-2470946Reactome: R-HSA-2500257 |
| Cellular Localisation | NucleusAssociated With Chromatin Through Most Of The Cell CycleDissociates From Chromatin In Late ProphaseReassociates During Late Telophase |
| Alternative Antibody Names | Anti-Sister Chromatid Cohesion Protein Pds5 Homolog A antibodyAnti-Cell Proliferation-Inducing Gene 54 Protein antibodyAnti-Sister Chromatid Cohesion Protein 112 antibodyAnti-Scc-112 antibodyAnti-PDS5A antibodyAnti-KIAA0648 antibodyAnti-PDS5 antibodyAnti-PIG54 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
