| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PDCD10 (1-212) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PDCD10 |
| Gene ID: |
11235 |
| Uniprot ID: |
PDC10_HUMAN |
| Immunogen Region: |
1-212 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human PDCD10 (NP_009148.2). |
| Immunogen Sequence: |
MRMTMEEMKNEAETTSMVSM PLYAVMYPVFNELERVNLSA AQTLRAAFIKAEKENPGLTQ DIIMKILEKKSVEVNFTESL LRMAADDVEEYMIERPEPEF QDLNEKARALKQILSKIPDE INDRVRFLQTIKDIASAIKE LLDTVNNVFKKYQYQNRRAL EHQKKEFVKYSKSFSDTLKT YFKDGKAINVFVSANRLIHQ TNLILQTFKTVA |
| Tissue Specificity | Ubiquitous. |
| Function | Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development. |
| Protein Name | Programmed Cell Death Protein 10Cerebral Cavernous Malformations 3 ProteinTf-1 Cell Apoptosis-Related Protein 15 |
| Cellular Localisation | CytoplasmGolgi Apparatus MembranePeripheral Membrane ProteinCytoplasmic SideCell MembranePartially Co-Localizes With Endogenous Pxn At The Leading Edges Of Migrating Cells |
| Alternative Antibody Names | Anti-Programmed Cell Death Protein 10 antibodyAnti-Cerebral Cavernous Malformations 3 Protein antibodyAnti-Tf-1 Cell Apoptosis-Related Protein 15 antibodyAnti-PDCD10 antibodyAnti-CCM3 antibodyAnti-TFAR15 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and PAK2 knockout (KO) HeLa cells, using [KO Validated] PAK2 Rabbit polyclonal antibody (STJ11100066) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89136/357585/STJ11100066_1__93634.1713121719.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and PAK2 knockout (KO) HeLa cells, using [KO Validated] PAK2 Rabbit polyclonal antibody (STJ11100066) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.")
