| Host: |
Rabbit |
| Applications: |
WB/IHC-P/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:1000-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PBXIP1 |
| Gene ID: |
57326 |
| Uniprot ID: |
PBIP1_HUMAN |
| Immunogen Region: |
1-190 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PBXIP1 (NP_065385.2). |
| Immunogen Sequence: |
MASCPDSDNSWVLAGSESLP VETLGPASRMDPESERALQA PHSPSKTDGKELAGTMDGEG TLFQTESPQSGSILTEETEV KGTLEGDVCGVEPPGPGDTV VQGDLQETTVVTGLGPDTQD LEGQSPPQSLPSTPKAAWIR EEGRCSSSDDDTDVDMEGLR RRRGREAGPPQPMVPLAVEN QAGGEGAGGE |
| Tissue Specificity | Expressed in early hematopoietic precursors. |
| Function | Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling. |
| Protein Name | Pre-B-Cell Leukemia Transcription Factor-Interacting Protein 1Hematopoietic Pbx-Interacting Protein |
| Cellular Localisation | CytoplasmCytoskeletonNucleusShuttles Between The Nucleus And The CytosolMainly Localized In The CytoplasmAssociated With MicrotubulesDetected In Small Amounts In The Nucleus |
| Alternative Antibody Names | Anti-Pre-B-Cell Leukemia Transcription Factor-Interacting Protein 1 antibodyAnti-Hematopoietic Pbx-Interacting Protein antibodyAnti-PBXIP1 antibodyAnti-HPIP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and MYOF knockout (KO) HeLa (KO) cells, using [KO Validated] MYOF Rabbit polyclonal antibody (STJ117622) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/96581/379140/STJ117622_1__97810.1713146869.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and MYOF knockout (KO) HeLa (KO) cells, using [KO Validated] MYOF Rabbit polyclonal antibody (STJ117622) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
