| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
PAXBP1 |
| Gene ID: |
94104 |
| Uniprot ID: |
PAXB1_HUMAN |
| Immunogen Region: |
200-300 aa |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human PAXBP1 (NP_057715.2). |
| Immunogen Sequence: |
TGGAFSNALSSLNVLRPGEI PDAAFIHAARKKRQMARELG DFTPHDNEPGKGRLVREDEN DASDDEDDDEKRRIVFSVKE KSQRQKIAEEIGIEGSDDDA L |
| Tissue Specificity | Ubiquitous. |
| Function | Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of 'Lys-4' of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20. |
| Protein Name | Pax3- And Pax7-Binding Protein 1Gc-Rich Sequence Dna-Binding Factor 1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pax3- And Pax7-Binding Protein 1 antibodyAnti-Gc-Rich Sequence Dna-Binding Factor 1 antibodyAnti-PAXBP1 antibodyAnti-C21orf66 antibodyAnti-GCFC antibodyAnti-GCFC1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
