Host: | Rabbit |
Applications: | WB/IF |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-PAH (1-290) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 IF/ICC 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | PAH |
Gene ID: | 5053 |
Uniprot ID: | PH4H_HUMAN |
Immunogen Region: | 1-290 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human PAH (NP_000268.1). |
Immunogen Sequence: | MSTAVLENPGLGRKLSDFGQ ETSYIEDNCNQNGAISLIFS LKEEVGALAKVLRLFEENDV NLTHIESRPSRLKKDEYEFF THLDKRSLPALTNIIKILRH DIGATVHELSRDKKKDTVPW FPRTIQELDRFANQILSYGA ELDADHPGFKDPVYRARRKQ FADIAYNYRHGQPIPRVEYM EEEKKTWGTVFKTLKSLYKT HACYEYNHIFPLLEKYCGFH EDNIPQLEDVSQFLQTCTG |
Post Translational Modifications | Phosphorylation at Ser-16 increases basal activity and facilitates activation by the substrate phenylalanine. |
Function | Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine. |
Protein Name | Phenylalanine-4-Hydroxylase Pah Phe-4-Monooxygenase |
Database Links | Reactome: R-HSA-2160456 Reactome: R-HSA-8964208 |
Alternative Antibody Names | Anti-Phenylalanine-4-Hydroxylase antibody Anti-Pah antibody Anti-Phe-4-Monooxygenase antibody Anti-PAH antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance