| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
P2RX3 |
| Gene ID: |
5024 |
| Uniprot ID: |
P2RX3_HUMAN |
| Immunogen Region: |
44-317 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 44-317 of human P2RX3 (NP_002550.2). |
| Immunogen Sequence: |
LHEKAYQVRDTAIESSVVTK VKGSGLYANRVMDVSDYVTP PQGTSVFVIITKMIVTENQM QGFCPESEEKYRCVSDSQCG PERLPGGGILTGRCVNYSSV LRTCEIQGWCPTEVDTVETP IMMEAENFTIFIKNSIRFPL FNFEKGNLLPNLTARDMKTC RFHPDKDPFCPILRVGDVVK FAGQDFAKLARTGGVLGIKI GWVCDLDKAWDQCIPKYSFT RLDSVSEKSSVSPGYNFRF |
| Function | Extracellular ATP-activated non-selective cation channel. Plays particularly important role in sensory neurons where its activation is critical for gustatory, nociceptive responses, visceral reflexes and sensory hypersensitization. |
| Protein Name | P2x Purinoceptor 3P2x3Atp ReceptorPurinergic Receptor |
| Database Links | Reactome: R-HSA-139853Reactome: R-HSA-418346 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLocalizes To Neuronal Cell Body Of Sensory Neurons |
| Alternative Antibody Names | Anti-P2x Purinoceptor 3 antibodyAnti-P2x3 antibodyAnti-Atp Receptor antibodyAnti-Purinergic Receptor antibodyAnti-P2RX3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
