Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-OSBPL10 (200-400) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
OSBPL10 |
Gene ID: |
114884 |
Uniprot ID: |
OSB10_HUMAN |
Immunogen Region: |
200-400 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human OSBPL10 (NP_060254.2). |
Immunogen Sequence: |
ASPCSQRHLSVGAPGVVTIT HHKSPAAARRAKSQYSGQLH EVREMMNQVEGQQKNLVHAI ESLPGSGPLTALDQDLLLLK ATSAATLSCLGECLNLLQQS VHQAGQPSQKPGASENILGW HGSKSHSTEQLKNGTLGSLP SASANITWAILPNSAEDEQT SQPEPEPNSGSELVLSEDEK SDNEDKEETELGVMEDQRSI I |
Function | Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P (Probable). Plays a role in negative regulation of lipid biosynthesis. Negatively regulates APOB secretion from hepatocytes. Binds cholesterol and acidic phospholipids. Also binds 25-hydroxycholesterol. Binds phosphatidylserine. |
Protein Name | Oxysterol-Binding Protein-Related Protein 10Orp-10Osbp-Related Protein 10 |
Database Links | Reactome: R-HSA-1482801 |
Cellular Localisation | CytoplasmCytoskeletonAssociates With Microtubules |
Alternative Antibody Names | Anti-Oxysterol-Binding Protein-Related Protein 10 antibodyAnti-Orp-10 antibodyAnti-Osbp-Related Protein 10 antibodyAnti-OSBPL10 antibodyAnti-ORP10 antibodyAnti-OSBP9 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance