| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-HBP1 (215-514) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HBP1 |
| Gene ID: |
26959 |
| Uniprot ID: |
HBP1_HUMAN |
| Immunogen Region: |
215-514 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 215-514 of human HBP1 (NP_036389.2). |
| Immunogen Sequence: |
FLKGTRLCFHKGSNKEWQDV EDFARAEGCDNEEDLQMGIH KGYGSDGLKLLSHEESVSFG ESVLKLTFDPGTVEDGLLTV ECKLDHPFYVKNKGWSSFYP SLTVVQHGIPCCEVHIGDVC LPPGHPDAINFDDSGVFDTF KSYDFTPMDSSAVYVLSSMA RQRRASLSCGGPGGQDFARS GFSKNCGSPGSSQLSSNSLY AKAVKNHSSGTVSATSPNKC KRPMNAFMLFAKKYRVEYT |
| Post Translational Modifications | Ubiquitinated by the CTLH E3 ubiquitin-protein ligase complex, leading to subsequent proteasomal degradation. |
| Function | Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. |
| Protein Name | Hmg Box-Containing Protein 1Hmg Box Transcription Factor 1High Mobility Group Box Transcription Factor 1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Hmg Box-Containing Protein 1 antibodyAnti-Hmg Box Transcription Factor 1 antibodyAnti-High Mobility Group Box Transcription Factor 1 antibodyAnti-HBP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
