Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-NUP210 (680-880) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:1000-1:2000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
NUP210 |
Gene ID: |
23225 |
Uniprot ID: |
PO210_HUMAN |
Immunogen Region: |
680-880 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 680-880 of human NUP210 (NP_079199.2). |
Immunogen Sequence: |
QNVTAEDTDSIGLALFAPHS SRNYQQHWILVTCQALGEQV IALSVGNKPSLTNPFPAVEP AVVKFVCAPPSRLTLAPVYT SPQLDMSCPLLQQNKQVVPV SSHRNPRLDLAAYDQEGRRF DNFSSLSIQWESTRPVLASI EPELPMQLVSQDDESGQKKL HGLQAILVHEASGTTAITAT ATGYQESHLSSARTKQPHDP L |
Tissue Specificity | Ubiquitous expression, with highest levels in lung, liver, pancreas, testis, and ovary, intermediate levels in brain, kidney, and spleen, and lowest levels in heart and skeletal muscle. |
Post Translational Modifications | N-glycosylated, but not all potential glycosylation sites may be used. Contains high-mannose type oligosaccharides. Phosphorylated at Ser-1881 in mitosis specifically.not phosphorylated in interphase. |
Function | Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. |
Protein Name | Nuclear Pore Membrane Glycoprotein 210Nuclear Pore Protein Gp210Nuclear Envelope Pore Membrane Protein Pom 210Pom210Nucleoporin Nup210Pore Membrane Protein Of 210 Kda |
Database Links | Reactome: R-HSA-1169408Reactome: R-HSA-159227Reactome: R-HSA-159230Reactome: R-HSA-159231Reactome: R-HSA-159236Reactome: R-HSA-165054Reactome: R-HSA-168271Reactome: R-HSA-168276Reactome: R-HSA-168325Reactome: R-HSA-168333Reactome: R-HSA-170822Reactome: R-HSA-180746Reactome: R-HSA-180910Reactome: R-HSA-191859Reactome: R-HSA-3108214Reactome: R-HSA-3232142Reactome: R-HSA-3301854Reactome: R-HSA-3371453Reactome: R-HSA-4085377Reactome: R-HSA-4551638Reactome: R-HSA-4570464Reactome: R-HSA-4615885Reactome: R-HSA-5578749Reactome: R-HSA-5619107Reactome: R-HSA-6784531Reactome: R-HSA-9609690Reactome: R-HSA-9610379Reactome: R-HSA-9705671 |
Cellular Localisation | NucleusNuclear Pore ComplexNucleus MembraneSingle-Pass Type I Membrane ProteinEndoplasmic Reticulum Membrane |
Alternative Antibody Names | Anti-Nuclear Pore Membrane Glycoprotein 210 antibodyAnti-Nuclear Pore Protein Gp210 antibodyAnti-Nuclear Envelope Pore Membrane Protein Pom 210 antibodyAnti-Pom210 antibodyAnti-Nucleoporin Nup210 antibodyAnti-Pore Membrane Protein Of 210 Kda antibodyAnti-NUP210 antibodyAnti-KIAA0906 antibodyAnti-PSEC0245 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance