| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NSMAF (1-300) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NSMAF |
| Gene ID: |
8439 |
| Uniprot ID: |
FAN_HUMAN |
| Immunogen Region: |
1-300 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NSMAF (NP_003571.2). |
| Immunogen Sequence: |
MAFIRKKQQEQQLQLYSKER FSLLLLNLEEYYFEQHRANH ILHKGSHHERKIRGSLKICS KSVIFEPDSISQPIIKIPLR DCIKIGKHGENGANRHFTKA KSGGISLIFSQVYFIKEHNV VAPYKIERGKMEYVFELDVP GKVEDVVETLLQLHRASCLD KLGDQTAMITAILQSRLART SFDKNRFQNISEKLHMECKA EMVTPLVTNPGHVCITDTNL YFQPLNGYPKPVVQITLQD |
| Tissue Specificity | Ubiquitous. |
| Function | Couples the p55 TNF-receptor (TNF-R55 / TNFR1) to neutral sphingomyelinase (N-SMASE). Specifically binds to the N-smase activation domain of TNF-R55. May regulate ceramide production by N-SMASE. |
| Protein Name | Protein FanFactor Associated With Neutral Sphingomyelinase ActivationFactor Associated With N-Smase Activation |
| Database Links | Reactome: R-HSA-5626978 |
| Alternative Antibody Names | Anti-Protein Fan antibodyAnti-Factor Associated With Neutral Sphingomyelinase Activation antibodyAnti-Factor Associated With N-Smase Activation antibodyAnti-NSMAF antibodyAnti-FAN antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and BUB1 knockout (KO) HeLa cells, using [KO Validated] BUB1 Rabbit polyclonal antibody (STJ11100026) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1min.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89098/357557/STJ11100026_1__69013.1713121681.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and BUB1 knockout (KO) HeLa cells, using [KO Validated] BUB1 Rabbit polyclonal antibody (STJ11100026) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1min.")
