Anti-NRF1 antibody (1-300) (STJ116123)

SKU:
STJ116123

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-NRF1 (1-300) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NRF1
Gene ID: 4899
Uniprot ID: NRF1_HUMAN
Immunogen Region: 1-300
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NRF1 (NP_001035199.1).
Immunogen Sequence: MEEHGVTQTEHMATIEAHAV AQQVQQVHVATYTEHSMLSA DEDSPSSPEDTSYDDSDILN STAADEVTAHLAAAGPVGMA AAAAVATGKKRKRPHVFESN PSIRKRQQTRLLRKLRATLD EYTTRVGQQAIVLCISPSKP NPVFKVFGAAPLENVVRKYK SMILEDLESALAEHAPAPQE VNSELPPLTIDGIPVSVDKM TQAQLRAFIPEMLKYSTGRG KPGWGKESCKPIWWPEDIP
Tissue Specificity Ubiquitously expressed with strongest expression in skeletal muscle.
Post Translational Modifications Phosphorylation enhances DNA binding.
Function Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.
Protein Name Nuclear Respiratory Factor 1
Nrf-1
Alpha Palindromic-Binding Protein
Alpha-Pal
Database Links Reactome: R-HSA-1989781
Reactome: R-HSA-2151201
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Nuclear Respiratory Factor 1 antibody
Anti-Nrf-1 antibody
Anti-Alpha Palindromic-Binding Protein antibody
Anti-Alpha-Pal antibody
Anti-NRF1 antibody

Information sourced from Uniprot.org

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