Tissue Specificity | Widely expressed. Detected in pancreas, liver, kidney, spleen, prostate, small intestine and colon. |
Post Translational Modifications | Interaction with YWHAZ depends on phosphorylation by PKA. |
Function | Functions as an activator of NOX1, a superoxide-producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction. May also activate CYBB/gp91phox and NOX3. |
Protein Name | Nadph Oxidase Activator 1Nox Activator 1Antigen Ny-Co-31Ncf2-Like ProteinP67phox-Like FactorP51-Nox |
Database Links | Reactome: R-HSA-5668599Reactome: R-HSA-9013149Reactome: R-HSA-9013423Reactome: R-HSA-9673324 |
Cellular Localisation | CytoplasmCell MembraneTranslocation To Membranes Depends On Noxo1 Or Ncf1 And Maybe Rac1 |
Alternative Antibody Names | Anti-Nadph Oxidase Activator 1 antibodyAnti-Nox Activator 1 antibodyAnti-Antigen Ny-Co-31 antibodyAnti-Ncf2-Like Protein antibodyAnti-P67phox-Like Factor antibodyAnti-P51-Nox antibodyAnti-NOXA1 antibodyAnti-P51NOX antibody |
Information sourced from Uniprot.org