| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NFKBIL1 (1-381) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NFKBIL1 |
| Gene ID: |
4795 |
| Uniprot ID: |
IKBL1_HUMAN |
| Immunogen Region: |
1-381 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-381 of human NFKBIL1 (NP_004998.3). |
| Immunogen Sequence: |
MSNPSPQVPEEEASTSVCRP KSSMASTSRRQRRERRFRRY LSAGRLVRAQALLQRHPGLD VDAGQPPPLHRACARHDAPA LCLLLRLGADPAHQDRHGDT ALHAAARQGPDAYTDFFLPL LSRCPSAMGIKNKDGETPGQ ILGWGPPWDSAEEEEEDDAS KEREWRQKLQGELEDEWQEV MGRFEGDASHETQEPESFSA WSDRLAREHAQKCQQQQREA EGSRRPPRAEGSSQSWRQQ |
| Tissue Specificity | Detected in different cell types including monocytes, T-cells, B-cells and hepatocytes. |
| Function | Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. |
| Protein Name | Nf-Kappa-B Inhibitor-Like Protein 1Inhibitor Of Kappa B-Like ProteinI-Kappa-B-Like ProteinIkappablNuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Inhibitor-Like 1 |
| Cellular Localisation | NucleusNuclear Localization With A Speckled Expression Pattern In Some CellsColocalizes With Cactin In The Nucleus |
| Alternative Antibody Names | Anti-Nf-Kappa-B Inhibitor-Like Protein 1 antibodyAnti-Inhibitor Of Kappa B-Like Protein antibodyAnti-I-Kappa-B-Like Protein antibodyAnti-Ikappabl antibodyAnti-Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Inhibitor-Like 1 antibodyAnti-NFKBIL1 antibodyAnti-IKBL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
