| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ADAP2 (1-381) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ADAP2 |
| Gene ID: |
55803 |
| Uniprot ID: |
ADAP2_HUMAN |
| Immunogen Region: |
1-381 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-381 of human ADAP2 (NP_060874.1). |
| Immunogen Sequence: |
MGDRERNKKRLLELLRAPDT GNAHCADCGAADPDWASYKL GIFICLNCCGVHRNFPDISR VKSVRLDFWDDSIVEFMIHN GNLRVKAKFEARVPAFYYIP QANDCLVLKEQWIRAKYERR EFMADGETISLPGNREGFLW KRGRDNSQFLRRKFVLLARE GLLKYFTKEQGKSPKAVISI KDLNATFQTEKIGHPHGLQI TYRRDGHTRNLFVYHESGKE IVDWFNALRAARLQYLKMA |
| Tissue Specificity | Highly expressed in placenta, spleen, kidney, skeletal muscle and adrenal gland. Weakly expressed in thyroid, liver, heart, lung, small intestine, peripheral blood leukocytes. Not detected in spinal cord, brain, stomach, trachea, colon, lymph node and bone marrow. |
| Function | GTPase-activating protein for the ADP ribosylation factor family (Potential). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). Possesses a stoichiometry of two binding sites for InsP4 with identical affinity. |
| Protein Name | Arf-Gap With Dual Ph Domain-Containing Protein 2Centaurin-Alpha-2Cnt-A2 |
| Cellular Localisation | CytoplasmCell MembraneConstitutively Associated With The Plasma MembraneExcluded From The Nucleus |
| Alternative Antibody Names | Anti-Arf-Gap With Dual Ph Domain-Containing Protein 2 antibodyAnti-Centaurin-Alpha-2 antibodyAnti-Cnt-A2 antibodyAnti-ADAP2 antibodyAnti-CENTA2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
