| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NFKBIL1 |
| Gene ID: | 4795 |
| Uniprot ID: | IKBL1_HUMAN |
| Immunogen Region: | 1-381 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-381 of human NFKBIL1 (NP_004998.3). |
| Immunogen Sequence: | MSNPSPQVPEEEASTSVCRP KSSMASTSRRQRRERRFRRY LSAGRLVRAQALLQRHPGLD VDAGQPPPLHRACARHDAPA LCLLLRLGADPAHQDRHGDT ALHAAARQGPDAYTDFFLPL LSRCPSAMGIKNKDGETPGQ ILGWGPPWDSAEEEEEDDAS KEREWRQKLQGELEDEWQEV MGRFEGDASHETQEPESFSA WSDRLAREHAQKCQQQQREA EGSRRPPRAEGSSQSWRQQ |
| Tissue Specificity | Detected in different cell types including monocytes, T-cells, B-cells and hepatocytes. |
| Function | Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. |
| Protein Name | Nf-Kappa-B Inhibitor-Like Protein 1Inhibitor Of Kappa B-Like ProteinI-Kappa-B-Like ProteinIkappablNuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Inhibitor-Like 1 |
| Cellular Localisation | NucleusNuclear Localization With A Speckled Expression Pattern In Some CellsColocalizes With Cactin In The Nucleus |
| Alternative Antibody Names | Anti-Nf-Kappa-B Inhibitor-Like Protein 1 antibodyAnti-Inhibitor Of Kappa B-Like Protein antibodyAnti-I-Kappa-B-Like Protein antibodyAnti-Ikappabl antibodyAnti-Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Inhibitor-Like 1 antibodyAnti-NFKBIL1 antibodyAnti-IKBL antibody |
Information sourced from Uniprot.org