Anti-NEUROD2 antibody (61-110) (STJ94427)

SKU:
STJ94427
£48.00 - £252.00
Processing The item has been added

Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Neurogenic differentiation factor 2 (61-110) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NEUROD2
Gene ID: 4761
Uniprot ID: NDF2_HUMAN
Immunogen Region: 61-110
Specificity: Neuro D2 Polyclonal Antibody detects endogenous levels of Neuro D2 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human NDF2. AA range:61-110
Function Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation.prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down-regulating REST expression. Plays a role in the establishment and maturation of thalamocortical connections.involved in the segregation of thalamic afferents into distinct barrel domains within layer VI of the somatosensory cortex. Involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis. Associates with chromatin to the DPYSL3 E box-containing promoter.
Protein Name Neurogenic Differentiation Factor 2
Neurod2
Class A Basic Helix-Loop-Helix Protein 1
Bhlha1
Neurod-Related Factor
Ndrf
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Neurogenic Differentiation Factor 2 antibody
Anti-Neurod2 antibody
Anti-Class A Basic Helix-Loop-Helix Protein 1 antibody
Anti-Bhlha1 antibody
Anti-Neurod-Related Factor antibody
Anti-Ndrf antibody
Anti-NEUROD2 antibody
Anti-BHLHA1 antibody
Anti-NDRF antibody

Information sourced from Uniprot.org