• Immunohistochemistry analysis of NEURL1B in paraffin-embedded rat kidney using NEURL1B Rabbit polyclonal antibody (STJ11103331) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of NEURL1B in paraffin-embedded mouse spinal cord using NEURL1B Rabbit polyclonal antibody (STJ11103331) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of lysates from Mouse brain, using NEURL1B Rabbit polyclonal antibody (STJ11103331) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Anti-NEURL1B antibody (270-440) (STJ11103331)

SKU:
STJ11103331

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-NEURL1B (270-440) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NEURL1B
Gene ID: 54492
Uniprot ID: NEU1B_HUMAN
Immunogen Region: 270-440
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 270-440 of human NEURL1B (NP_001136123.1).
Immunogen Sequence: ASSPALLEADLRFHATRGPD VSLSADRKVACAPRPDGGRT LVFSERPLRPGESLFVEVGR PGLAAPGALAFGITSCDPGV LRPNELPADPDALLDRKEYW VVARAGPVPSGGDALSFTLR PGGDVLLGINGRPRGRLLCV DTTQALWAFFAVRGGVAGQL RLLGTLQSSPA
Tissue Specificity Highest expression in brain, prostate and small intestine. In the brain the levels are higher in fetal than in adult stage. In the adult brain the highest levels are detected in the olfactory system, cerebellar cortex, optic nerve and the frontal lobe.
Function E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands.
Protein Name E3 Ubiquitin-Protein Ligase Neurl1b
Neuralized-2
Neur2
Neuralized-Like Protein 1b
Neuralized-Like Protein 3
Ring-Type E3 Ubiquitin Transferase Neurl1b
Database Links Reactome: R-HSA-2122948
Reactome: R-HSA-2644606
Reactome: R-HSA-2691232
Reactome: R-HSA-2894862
Reactome: R-HSA-2979096
Reactome: R-HSA-9013507
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-E3 Ubiquitin-Protein Ligase Neurl1b antibody
Anti-Neuralized-2 antibody
Anti-Neur2 antibody
Anti-Neuralized-Like Protein 1b antibody
Anti-Neuralized-Like Protein 3 antibody
Anti-Ring-Type E3 Ubiquitin Transferase Neurl1b antibody
Anti-NEURL1B antibody
Anti-NEURL3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance