| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NEO1 (160-340) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NEO1 |
| Gene ID: |
4756 |
| Uniprot ID: |
NEO1_HUMAN |
| Immunogen Region: |
160-340 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 160-340 of human NEO1 (NP_002490.2). |
| Immunogen Sequence: |
PSSVYAGNNAILNCEVNADL VPFVRWEQNRQPLLLDDRVI KLPSGMLVISNATEGDGGLY RCVVESGGPPKYSDEVELKV LPDPEVISDLVFLKQPSPLV RVIGQDVVLPCVASGLPTPT IKWMKNEEALDTESSERLVL LAGGSLEISDVTEDDAGTYF CIADNGNETIEAQAELTVQA Q |
| Tissue Specificity | Widely expressed and also in cancer cell lines. |
| Function | Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes, including neural tube and mammary gland formation, myogenesis and angiogenesis. Receptor for members of the BMP, netrin, and repulsive guidance molecule (RGM) families. Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion, the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive response. |
| Protein Name | NeogeninImmunoglobulin Superfamily Dcc Subclass Member 2 |
| Database Links | Reactome: R-HSA-373752Reactome: R-HSA-525793 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Neogenin antibodyAnti-Immunoglobulin Superfamily Dcc Subclass Member 2 antibodyAnti-NEO1 antibodyAnti-IGDCC2 antibodyAnti-NGN antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
