| Tissue Specificity | Highest expression in thyroid, adrenal gland and skin. Low levels in spleen, colon and uterus. Overexpressed in breast tumors, with highest expression in infiltrating ductal carcinomas and moderate levels in mucinous adenocarcinoma. |
| Function | Required for renal tubular integrity. May regulate local cytoskeletal structure in kidney tubule epithelial cells. May regulate ciliary biogenesis through targeting of proteins to the cilia. Plays a role in organogenesis, and is involved in the regulation of the Hippo signaling pathway. |
| Protein Name | Serine/Threonine-Protein Kinase Nek8Never In Mitosis A-Related Kinase 8Nima-Related Protein Kinase 8Nima-Related Protein Kinase 12a |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionCiliumMicrotubule Organizing CenterCentrosomeCilium AxonemePredominantly CytoplasmicLocalizes To The Proximal Region Of The Primary Cilium And Is Not Observed In Dividing Cells |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase Nek8 antibodyAnti-Never In Mitosis A-Related Kinase 8 antibodyAnti-Nima-Related Protein Kinase 8 antibodyAnti-Nima-Related Protein Kinase 12a antibodyAnti-NEK8 antibodyAnti-JCK antibodyAnti-NEK12A antibody |
Information sourced from Uniprot.org
