| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Nuclear receptor coactivator 5 (345-394) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NCOA5 |
| Gene ID: | 57727 |
| Uniprot ID: | NCOA5_HUMAN |
| Immunogen Region: | 345-394 |
| Specificity: | NCoA-5 Polyclonal Antibody detects endogenous levels of NCoA-5 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human NCOA5. AA range:345-394 |
| Tissue Specificity | Widely expressed. |
| Function | Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC in response to 17-beta-estradiol (E2). |
| Protein Name | Nuclear Receptor Coactivator 5Ncoa-5Coactivator Independent Of Af-2Cia |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Nuclear Receptor Coactivator 5 antibodyAnti-Ncoa-5 antibodyAnti-Coactivator Independent Of Af-2 antibodyAnti-Cia antibodyAnti-NCOA5 antibodyAnti-KIAA1637 antibody |
Information sourced from Uniprot.org