| Host: |
Rabbit |
| Applications: |
IF |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NAT8B (75-165) is suitable for use in Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NAT8BUniprot ID=NAT8B_HUMAN" |
| Immunogen Region: |
75-165 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 75-165 of human NAT8B (NP_057431.2). |
| Immunogen Sequence: |
WFLAKKPWTRYVDIALRTDM SDITKSYLSECGSCFWVGES EEKVVGTVGALPVDDPTLRE KRLQLFHLSVDNEHRGQGIA KALVRTVLQFA |
| Function | Lysine N-acetyltransferase catalyzing peptidyl-lysine N6-acetylation of various proteins, including PROM1/CD133. Thereby, may regulate apoptosis through the acetylation and the regulation of the expression of PROM1. Acetylates and stabilizes BACE1 immature protein, leading to increased steady-state levels in neurons. By acting on BACE1 expression, may regulate amyloid beta-peptide formation. May play a role in regulation of gastrulation. |
| Protein Name | Putative N-Acetyltransferase 8bAcetyltransferase 1Atase1Camello-Like Protein 2 |
| Cellular Localisation | Endoplasmic Reticulum-Golgi Intermediate Compartment MembraneSingle-Pass Type Ii Membrane ProteinEndoplasmic Reticulum MembraneEnriched In The Endoplasmic Reticulum-Golgi Intermediate Compartment (Ergic) |
| Alternative Antibody Names | Anti-Putative N-Acetyltransferase 8b antibodyAnti-Acetyltransferase 1 antibodyAnti-Atase1 antibodyAnti-Camello-Like Protein 2 antibodyAnti-NAT8B antibodyAnti-CML2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
