• Western blot analysis of various lysates using MYOZ1 Rabbit polyclonal antibody (STJ116693) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 30s.

Anti-MYOZ1 antibody (180-299) (STJ116693)

SKU:
STJ116693

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MYOZ1 (180-299) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MYOZ1
Gene ID: 58529
Uniprot ID: MYOZ1_HUMAN
Immunogen Region: 180-299
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-299 of human MYOZ1 (NP_067068.1).
Immunogen Sequence: VFKTYISPWERAMGVDPQQK MELGIDLLAYGAKAELPKYK SFNRTAMPYGGYEKASKRMT FQMPKFDLGPLLSEPLVLYN QNLSNRPSFNRTPIPWLSSG EPVDYNVDIGIPLDGETEEL
Tissue Specificity Expressed primarily in skeletal muscle. Detected at lower levels in heart, prostate and pancreas.
Function Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.
Protein Name Myozenin-1
Calsarcin-2
Filamin- - Actinin- And Telethonin-Binding Protein
Protein Fatz
Cellular Localisation Nucleus
Cell Projection
Pseudopodium
Localized To The Nucleus And Pseudopodia Of Undifferentiated Cells And Detected Throughout The Myotubes Of Differentiated Cells
Colocalizes With Actn2
Flnc And Myot At The Z-Lines Of Skeletal Muscle
Alternative Antibody Names Anti-Myozenin-1 antibody
Anti-Calsarcin-2 antibody
Anti-Filamin- - Actinin- And Telethonin-Binding Protein antibody
Anti-Protein Fatz antibody
Anti-MYOZ1 antibody
Anti-MYOZ antibody

Information sourced from Uniprot.org

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