| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MYBL1 (443-692) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MYBL1 |
| Gene ID: |
4603 |
| Uniprot ID: |
MYBA_HUMAN |
| Immunogen Region: |
443-692 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 443-692 of human MYBL1 (NP_001138227.1). |
| Immunogen Sequence: |
PPAILRKKRKMRVGHSPGSE LRDGSLNDGGNMALKHTPLK TLPFSPSQFFNTCPGNEQLN IENPSFTSTPICGQKALITT PLHKETTPKDQKENVGFRTP TIRRSILGTTPRTPTPFKNA LAAQEKKYGPLKIVSQPLAF LEEDIREVLKEETGTDLFLK EEDEPAYKSCKQENTASGKK VRKSLVLDNWEKEESGTQLL TEDISDMQSNCEWETVVYGK TEDQLIMTEQARRYLSTYT |
| Tissue Specificity | Expressed in a variety of lymphoid and solid tumor lines cultured in vitro. |
| Function | Transcription factor that specifically recognizes the sequence 5'-YAACGTG-3'. Acts as a master regulator of male meiosis by promoting expression of piRNAs: activates expression of both piRNA precursor RNAs and expression of protein-coding genes involved in piRNA metabolism. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity. Transcriptional activator of SOX30. |
| Protein Name | Myb-Related Protein AA-MybMyb-Like Protein 1 |
| Database Links | Reactome: R-HSA-5601884 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Myb-Related Protein A antibodyAnti-A-Myb antibodyAnti-Myb-Like Protein 1 antibodyAnti-MYBL1 antibodyAnti-AMYB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
