• Confocal immunofluorescence analysis of U2OS cells using MTX1 Rabbit polyclonal antibody (STJ11104376) at dilution of 1:100. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of U2OS cells using MTX1 Rabbit polyclonal antibody (STJ11104376) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Western blot analysis of various lysates using MTX1 Rabbit polyclonal antibody (STJ11104376) at 1:1000 dilution. _Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. _Lysates/proteins: 25 Mu g per lane. _Blocking buffer: 3% nonfat dry milk in TBST. _Detection: ECL Enhanced Kit. _Exposure time: 90s.

Anti-MTX1 antibody (186-435) (STJ11104376)

SKU:
STJ11104376

£112.50 - £522.50
Current Stock:
Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Metaxin-1 (186-435) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MTX1
Gene ID: 4580
Uniprot ID: MTX1_HUMAN
Immunogen Region: 186-435
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 186-435 of human MTX1 (NP_942584.2).
Immunogen Sequence: LKVHKISNPWQSPSGTLPAL RTSHGEVISVPHKIITHLRK EVHTFWIDTKNYVEVTRKWY AEAMPFPLNFFLPGRMQRQY MERLQLLTGEHRPEDEEELE KELYREARECLTLLSQRLGS QKFFFGDAPASLDAFVFSYL ALLLQAKLPSGKLQVHLRGL HNLCAYCTHILSLYFPWDGA EVPPQRQTPAGPETEEEPYR RRNQILSVLAGLAAMVGYAL LSGIVSIQRATPARAPGTR
Post Translational Modifications Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30.
Function Involved in transport of proteins into the mitochondrion. Essential for embryonic development.
Protein Name Metaxin-1
Mitochondrial Outer Membrane Import Complex Protein 1
Database Links Reactome: R-HSA-1268020
Reactome: R-HSA-8949613
Reactome: R-HSA-9013404
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Mitochondrion Outer Membrane
Alternative Antibody Names Anti-Metaxin-1 antibody
Anti-Mitochondrial Outer Membrane Import Complex Protein 1 antibody
Anti-MTX1 antibody
Anti-MTX antibody
Anti-MTXN antibody

Information sourced from Uniprot.org

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