| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MTO1 |
| Gene ID: | 25821 |
| Uniprot ID: | MTO1_HUMAN |
| Immunogen Region: | 420-680 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 420-680 of human MTO1 (NP_036255.2). |
| Immunogen Sequence: | QGVIAGINASLRVSRKPPFV VSRTEGYIGVLIDDLTTLGT SEPYRMFTSRVEFRLSLRPD NADSRLTLRGYKDAGCVSQQ RYERACWMKSSLEEGISVLK SIEFLSSKWKKLIPEASIST SRSLPVRALDVLKYEEVDMD SLAKAVPEPLKKYTKCRELA ERLKIEATYESVLFHQLQEI KGVQQDEALQLPKDLDYLTI RDVSLSHEVREKLHFSRPQT IGAASRIPGVTPAAIINLL |
| Tissue Specificity | Ubiquitously expressed in various tissues, but with a markedly elevated expression in tissues of high metabolic rates including cochlea. |
| Function | Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs. |
| Protein Name | Protein Mto1 Homolog - Mitochondrial |
| Database Links | Reactome: R-HSA-6787450 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Protein Mto1 Homolog - Mitochondrial antibodyAnti-MTO1 antibodyAnti-CGI-02 antibody |
Information sourced from Uniprot.org