| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MTERFD1 (69-300) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MTERF3 |
| Gene ID: |
51001 |
| Uniprot ID: |
MTEF3_HUMAN |
| Immunogen Region: |
69-300 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 69-300 of human MTERFD1 (NP_057026.3). |
| Immunogen Sequence: |
SSQSTSSSSQENNSAQSSLL PSMNEQSQKTQNISSFDSEL FLEELDELPPLSPMQPISEE EAIQIIADPPLPPASFTLRD YVDHSETLQKLVLLGVDLSK IEKHPEAANLLLRLDFEKDI KQMLLFLKDVGIEDNQLGAF LTKNHAIFSEDLENLKTRVA YLHSKNFSKADVAQMVRKAP FLLNFSVERLDNRLGFFQKE LELSVKKTRDLVVRLPRLLT GSLEPVKENMKV |
| Tissue Specificity | Highly expressed in heart, liver, kidney and testis. Detected at lower levels in brain, spleen and lung. |
| Function | Binds promoter DNA and regulates initiation of transcription. Required for normal mitochondrial transcription and translation, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function. Maintains 16S rRNA levels and functions in mitochondrial ribosome assembly by regulating the biogenesis of the 39S ribosomal subunit. |
| Protein Name | Transcription Termination Factor 3 - MitochondrialMitochondrial Transcription Termination Factor 3Mterf3Mterf Domain-Containing Protein 1 - Mitochondrial |
| Database Links | Reactome: R-HSA-5205685 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Transcription Termination Factor 3 - Mitochondrial antibodyAnti-Mitochondrial Transcription Termination Factor 3 antibodyAnti-Mterf3 antibodyAnti-Mterf Domain-Containing Protein 1 - Mitochondrial antibodyAnti-MTERF3 antibodyAnti-MTERFD1 antibodyAnti-CGI-12 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
