• Western blot analysis of extracts of HeLa cells, using MSH2 antibody (STJ24610).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

Anti-MSH2 antibody (STJ24610)

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Host: Rabbit
Applications: WB, IF, FC
Reactivity: Human
Short Description: Rabbit polyclonal primary antibody against MSH2.
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: PBS with 0.02% sodium azide, pH7.3.
Purification: Affinity purification
Storage Instruction: Store at 4°C. Avoid freeze/thaw cycles.
Isotype: IgG
Dilution Range: WB: 1:500-1:1000
IF: 1:20-1:50
FC: 1:20-1:50
Uniprot ID: MSH2_HUMAN
Gene ID: 4436
Gene Symbol: MSH2
Immunogen: A synthetic peptide of human MSH2
Background This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
Tissue Specificity Ubiquitously expressed.
Post Translational Modifications Phosphorylated by PRKCZ, which may prevent MutS alpha degradation by the ubiquitin-proteasome pathway.
Database Links Reactome: R-HSA-5358565
Cellular Localisation Nucleus
Protein Name Dna Mismatch Repair Protein Msh2
Muts Protein Homolog 2
Alternative Names Anti-Dna Mismatch Repair Protein Msh2 antibody
Anti-Hmsh2 antibody
Anti-Muts Protein Homolog 2 antibody
Anti-MSH2 antibody

Information sourced from uniprot.org

6 months standard