| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MRM1 (1-353) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MRM1 |
| Gene ID: |
79922 |
| Uniprot ID: |
MRM1_HUMAN |
| Immunogen Region: |
1-353 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-353 of human MRM1 (NP_079140.2). |
| Immunogen Sequence: |
MALLSTVRGATWGRLVTRHF SHAARHGERPGGEELSRLLL DDLVPTSRLELLFGMTPCLL ALQAARRSVARLLLQAGKAG LQGKRAELLRMAEARDIPVL RPRRQKLDTMCRYQVHQGVC MEVSPLRPRPWREAGEASPG DDPQQLWLVLDGIQDPRNFG AVLRSAHFLGVDKVITSRRN SCPLTPVVSKSSAGAMEVMD VFSTDDLTGFLQTKAQQGWL VAGTVGCPSTEDPQSSEIP |
| Function | S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1145 (Gm1145) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. |
| Protein Name | Rrna Methyltransferase 1 - Mitochondrial16s RrnaGuanosine(1145-2'-O-Methyltransferase16s Rrna Gm1145 2'-O-Methyltransferase |
| Database Links | Reactome: R-HSA-6793080 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Rrna Methyltransferase 1 - Mitochondrial antibodyAnti-16s Rrna antibodyAnti-Guanosine(1145-2'-O-Methyltransferase antibodyAnti-16s Rrna Gm1145 2'-O-Methyltransferase antibodyAnti-MRM1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Immunofluorescence analysis of PC-12 cells using [KO Validated] PTPN2 Rabbit polyclonal antibody (STJ25225) at dilution of 1:200 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/100383/386780/STJ25225_1__40369.1713155922.jpg?c=1 "Immunofluorescence analysis of PC-12 cells using [KO Validated] PTPN2 Rabbit polyclonal antibody (STJ25225) at dilution of 1:200 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.")
