| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | Mmp9 |
| Gene ID: | 17395 |
| Uniprot ID: | MMP9_MOUSE |
| Immunogen Region: | 1-150 |
| Specificity: | Recombinant Protein corresponding to a sequence within amino acids 108-730 of mouse MMP9 (NP_038627.1). |
| Immunogen Sequence: | FQTFKGLKWDHHNITYWIQN YSEDLPRDMIDDAFARAFAV WGEVAPLTFTRVYGPEADIV IQFGVAEHGDGYPFDGKDGL LAHAFPPGAGVQGDAHFDDD ELWSLGKGVVIPTYYGNSNG APCHFPFTFEGRSYSACTTD GRNDGTPWCSTTADYDKDGK FGFCPSERLYTEHGNGEGKP CVFPFIFEGRSYSACTTKGR SDGYRWCATTANYDQDKLYG FCPTRVDATVVGGNSAGEL |
| Post Translational Modifications | N- and O-glycosylated. |
| Function | Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. |
| Protein Name | Matrix Metalloproteinase-9Mmp-992 Kda Gelatinase92 Kda Type Iv CollagenaseGelatinase BGelb |
| Database Links | Reactome: R-MMU-1433557Reactome: -MMU-1442490Reactome: -MMU-1474228Reactome: -MMU-1592389Reactome: -MMU-2022090Reactome: -MMU-3928665Reactome: -MMU-6798695Reactome: -MMU-9009391 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Matrix Metalloproteinase-9 antibodyAnti-Mmp-9 antibodyAnti-92 Kda Gelatinase antibodyAnti-92 Kda Type Iv Collagenase antibodyAnti-Gelatinase B antibodyAnti-Gelb antibodyAnti-Mmp9 antibodyAnti-Clg4b antibody |
Information sourced from Uniprot.org