| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MLC1 |
| Gene ID: | 23209 |
| Uniprot ID: | MLC1_HUMAN |
| Immunogen Region: | C-Term |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human MLC1 (NP_055981.1). |
| Immunogen Sequence: | SYDVLLLLLLLVLLLQAGLN TGTAIQCVRFKVSARLQGAS WDTQNGPQERLAGEVARSPL KEFDKEKAWRAVVVQMAQ |
| Tissue Specificity | Expressed in the brain, with highest levels found in the amygdala, nucleus caudatus, thalamus and hippocampus. |
| Function | Transmembrane protein mainly expressed in brain atrocytes that may play a role in transport across the blood-brain and brain-cerebrospinal fluid barriers. Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx. May function as regulatory protein of membrane protein complexes such as ion channels (Probable). |
| Protein Name | Membrane Protein Mlc1Megalencephalic Leukoencephalopathy With Subcortical Cysts Protein 1 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCell MembraneCytoplasmPerinuclear RegionEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Membrane Protein Mlc1 antibodyAnti-Megalencephalic Leukoencephalopathy With Subcortical Cysts Protein 1 antibodyAnti-MLC1 antibodyAnti-KIAA0027 antibodyAnti-WKL1 antibody |
Information sourced from Uniprot.org