| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MGAT5B |
| Gene ID: | 146664 |
| Uniprot ID: | MGT5B_HUMAN |
| Immunogen Region: | 616-790 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 616-790 of human MGAT5B (NP_653278.2). |
| Immunogen Sequence: | DPYLPYEYTCEGMLERIHAY IQHQDFCRAPDPALPEAHAP QSPFVLAPNATHLEWARNTS LAPGAWPPAHALRAWLAVPG RACTDTCLDHGLICEPSFFP FLNSQDAFLKLQVPCDSTES EMNHLYPAFAQPGQECYLQK EPLLFSCAGSNTKYRRLCPC RDFRKGQVALCQGCL |
| Tissue Specificity | Predominantly expressed in brain. Expressed in all areas of the adult and fetal brain. Also expressed at much lower levels in testis, spleen and thymus. |
| Function | Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAc-beta1,2-Man-alpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAc-beta1,2-Man-alpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway. |
| Protein Name | Alpha-1 -6-Mannosylglycoprotein 6-Beta-N-Acetylglucosaminyltransferase B Alpha-Mannoside Beta-1 -6-N-Acetylglucosaminyltransferase B Glcnac-T Vb Gnt-Vb Hgntvb Mannoside Acetylglucosaminyltransferase 5b N-Acetylglucosaminyl-Transferase Vb N-Acetylglucosaminyltransferase Ix Gnt-Ix |
| Cellular Localisation | Golgi Apparatus Membrane Single-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Alpha-1 -6-Mannosylglycoprotein 6-Beta-N-Acetylglucosaminyltransferase B antibody Anti-Alpha-Mannoside Beta-1 -6-N-Acetylglucosaminyltransferase B antibody Anti-Glcnac-T Vb antibody Anti-Gnt-Vb antibody Anti-Hgntvb antibody Anti-Mannoside Acetylglucosaminyltransferase 5b antibody Anti-N-Acetylglucosaminyl-Transferase Vb antibody Anti-N-Acetylglucosaminyltransferase Ix antibody Anti-Gnt-Ix antibody Anti-MGAT5B antibody Anti-KIAA2008 antibody |
Information sourced from Uniprot.org