| Tissue Specificity | Predominantly expressed in brain. Expressed in all areas of the adult and fetal brain. Also expressed at much lower levels in testis, spleen and thymus. |
| Function | Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAc-beta1,2-Man-alpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAc-beta1,2-Man-alpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway. |
| Protein Name | Alpha-1 -6-Mannosylglycoprotein 6-Beta-N-Acetylglucosaminyltransferase BAlpha-Mannoside Beta-1 -6-N-Acetylglucosaminyltransferase BGlcnac-T VbGnt-VbHgntvbMannoside Acetylglucosaminyltransferase 5bN-Acetylglucosaminyl-Transferase VbN-Acetylglucosaminyltransferase IxGnt-Ix |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Alpha-1 -6-Mannosylglycoprotein 6-Beta-N-Acetylglucosaminyltransferase B antibodyAnti-Alpha-Mannoside Beta-1 -6-N-Acetylglucosaminyltransferase B antibodyAnti-Glcnac-T Vb antibodyAnti-Gnt-Vb antibodyAnti-Hgntvb antibodyAnti-Mannoside Acetylglucosaminyltransferase 5b antibodyAnti-N-Acetylglucosaminyl-Transferase Vb antibodyAnti-N-Acetylglucosaminyltransferase Ix antibodyAnti-Gnt-Ix antibodyAnti-MGAT5B antibodyAnti-KIAA2008 antibody |
Information sourced from Uniprot.org
