| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MAP3K2 (1-180) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MAP3K2 |
| Gene ID: |
10746 |
| Uniprot ID: |
M3K2_HUMAN |
| Immunogen Region: |
1-180 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human MEKK2 (NP_006600.3). |
| Immunogen Sequence: |
MDDQQALNSIMQDLAVLHKA SRPALSLQETRKAKSSSPKK QNDVRVKFEHRGEKRILQFP RPVKLEDLRSKAKIAFGQSM DLHYTNNELVIPLTTQDDLD KAVELLDRSIHMKSLKILLV INGSTQATNLEPLPSLEDLD NTVFGAERKKRLSIIGPTSR DRSSPPPGYIPDELHQVARN |
| Post Translational Modifications | Autophosphorylated. Ubiquitination by XIAP/BIRC4 does not lead to proteasomal degradation. |
| Function | Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7. Plays a role in caveolae kiss-and-run dynamics. |
| Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 2Mapk/Erk Kinase Kinase 2Mek Kinase 2Mekk 2 |
| Cellular Localisation | CytoplasmNucleusUpon Egf StimulationTranslocates Into The Nucleus |
| Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 antibodyAnti-Mapk/Erk Kinase Kinase 2 antibodyAnti-Mek Kinase 2 antibodyAnti-Mekk 2 antibodyAnti-MAP3K2 antibodyAnti-MAPKKK2 antibodyAnti-MEKK2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
