| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MAP1S (830-1059) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MAP1S |
| Gene ID: |
55201 |
| Uniprot ID: |
MAP1S_HUMAN |
| Immunogen Region: |
830-1059 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 830-1059 of human MAP1S (NP_060644.4). |
| Immunogen Sequence: |
VPPPLPDPSSICMVDPEMLP PKTARQTENVSRTRKPLARP NSRAAAPKATPVAAAKTKGL AGGDRASRPLSARSEPSEKG GRAPLSRKSSTPKTATRGPS GSASSRPGVSATPPKSPVYL DLAYLPSGSSAHLVDEEFFQ RVRALCYVISGQDQRKEEGM RAVLDALLASKQHWDRDLQV TLIPTFDSVAMHTWYAETHA RHQALGITVLGSNSMVSMQD DAFPACKVEF |
| Tissue Specificity | Expressed in neurons (at protein level). Expressed in spermatocytes, spermatids and spermatozoa. Expressed in the cerebral cortex. Highly expressed in testis. Moderately expressed in the brain, colon, heart, kidney, liver, lung, placenta, small intestine, spleen and stomach. Weakly expressed in muscle. |
| Function | Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles. |
| Protein Name | Microtubule-Associated Protein 1sMap-1sBpy2-Interacting Protein 1Microtubule-Associated Protein 8Variable Charge Y Chromosome 2-Interacting Protein 1Vcy2-Interacting Protein 1Vcy2ip-1 Cleaved Into - Map1s Heavy Chain - Map1s Light Chain |
| Cellular Localisation | NucleusCytoplasmCytosolCytoskeletonSpindleDetected In Filopodia-Like Protrusions And SynapsesDetected In Perinuclear Punctate Network Corresponding To Mitochondrial Aggregates And In The Nucleus In Cells Exhibiting ApoptosisAssociated Specifically With Microtubules Stabilized By Paclitaxel And Colocalizes With Rassf1 Isoform AIn Interphase CellsShows A Diffuse Cytoplasmic Staining With Partial Localization To The MicrotubulesDuring The Different Stages Of Mitosis Detected At The Spindle Microtubules |
| Alternative Antibody Names | Anti-Microtubule-Associated Protein 1s antibodyAnti-Map-1s antibodyAnti-Bpy2-Interacting Protein 1 antibodyAnti-Microtubule-Associated Protein 8 antibodyAnti-Variable Charge Y Chromosome 2-Interacting Protein 1 antibodyAnti-Vcy2-Interacting Protein 1 antibodyAnti-Vcy2ip-1 Cleaved Into - Map1s Heavy Chain - Map1s Light Chain antibodyAnti-MAP1S antibodyAnti-BPY2IP1 antibodyAnti-C19orf5 antibodyAnti-MAP8 antibodyAnti-VCY2IP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
