• Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-MAP1B antibody (480-560 aa) (STJ190960)

SKU:
STJ190960

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Microtubule-associated protein 1B (480-560 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-300
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MAP1B
Gene ID: 4131
Uniprot ID: MAP1B_HUMAN
Immunogen Region: 480-560 aa
Specificity: MAP1B Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from the human protein at the amino acid range 480-560
Function Facilitates tyrosination of alpha-tubulin in neuronal microtubules. Phosphorylated MAP1B is required for proper microtubule dynamics and plays a role in the cytoskeletal changes that accompany neuronal differentiation and neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.
Protein Name Microtubule-Associated Protein 1b
Map-1b Cleaved Into - Map1b Heavy Chain - Map1 Light Chain Lc1
Cellular Localisation Cytoplasm
Cytoskeleton
Synapse
Cell Projection
Dendritic Spine
Colocalizes With Dapk1 In The Microtubules And Cortical Actin Fibers
Map1 Light Chain Lc1: Cytoplasm
Alternative Antibody Names Anti-Microtubule-Associated Protein 1b antibody
Anti-Map-1b Cleaved Into - Map1b Heavy Chain - Map1 Light Chain Lc1 antibody
Anti-MAP1B antibody

Information sourced from Uniprot.org

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