| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LYPD3 (31-326) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LYPD3 |
| Gene ID: |
27076 |
| Uniprot ID: |
LYPD3_HUMAN |
| Immunogen Region: |
31-326 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 31-326 of human LYPD3 (NP_055215.2). |
| Immunogen Sequence: |
LECYSCVQKADDGCSPNKMK TVKCAPGVDVCTEAVGAVET IHGQFSLAVRGCGSGLPGKN DRGLDLHGLLAFIQLQQCAQ DRCNAKLNLTSRALDPAGNE SAYPPNGVECYSCVGLSREA CQGTSPPVVSCYNASDHVYK GCFDGNVTLTAANVTVSLPV RGCVQDEFCTRDGVTGPGFT LSGSCCQGSRCNSDLRNKTY FSPRIPPLVRLPPPEPTTVA STTSVTTSTSAPVRPTSTT |
| Tissue Specificity | Expressed in placenta, skin and urothelium. Found in suprabasal keratinocytes of chronic wounds. Weak expression is found in esophagus and peripheral blood mononuclear cells. Found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression is found in the tumor component of some noninvasive superficial lesions and in invasive and metastatic urothelial cancers. |
| Post Translational Modifications | N-glycosylated and O-glycosylated. |
| Function | Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression. |
| Protein Name | Ly6/Plaur Domain-Containing Protein 3Gpi-Anchored Metastasis-Associated Protein C4.4a HomologMatrigel-Induced Gene C4 ProteinMig-C4 |
| Database Links | Reactome: R-HSA-163125 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Ly6/Plaur Domain-Containing Protein 3 antibodyAnti-Gpi-Anchored Metastasis-Associated Protein C4.4a Homolog antibodyAnti-Matrigel-Induced Gene C4 Protein antibodyAnti-Mig-C4 antibodyAnti-LYPD3 antibodyAnti-C4.4A antibodyAnti-UNQ491 antibodyAnti-PRO1007 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
