Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-LTBR (249-435) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
LTBR |
Gene ID: |
4055 |
Uniprot ID: |
TNR3_HUMAN |
Immunogen Region: |
249-435 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 249-435 of human LTBR (NP_002333.1). |
Immunogen Sequence: |
KSHPSLCRKLGSLLKRRPQG EGPNPVAGSWEPPKAHPYFP DLVQPLLPISGDVSPVSTGL PAAPVLEAGVPQQQSPLDLT REPQLEPGEQSQVAHGTNGI HVTGGSMTITGNIYIYNGPV LGGPPGPGDLPATPEPPYPI PEEGDPGPPGLSTPHQEDGK AWHLAETEHCGATPSNRGPR NQFITHD |
Function | Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 3Lymphotoxin-Beta ReceptorTumor Necrosis Factor C ReceptorTumor Necrosis Factor Receptor 2-Related ProteinTumor Necrosis Factor Receptor Type IiiTnf-RiiiTnfr-Iii |
Database Links | Reactome: R-HSA-5668541Reactome: R-HSA-5676594 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 3 antibodyAnti-Lymphotoxin-Beta Receptor antibodyAnti-Tumor Necrosis Factor C Receptor antibodyAnti-Tumor Necrosis Factor Receptor 2-Related Protein antibodyAnti-Tumor Necrosis Factor Receptor Type Iii antibodyAnti-Tnf-Riii antibodyAnti-Tnfr-Iii antibodyAnti-LTBR antibodyAnti-D12S370 antibodyAnti-TNFCR antibodyAnti-TNFR3 antibodyAnti-TNFRSF3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance